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Katherine T Dawson Selected Research

Dimethyl Fumarate

12/2017Evidence of activation of the Nrf2 pathway in multiple sclerosis patients treated with delayed-release dimethyl fumarate in the Phase 3 DEFINE and CONFIRM studies.
3/2015Effects of delayed-release dimethyl fumarate on MRI measures in the phase 3 CONFIRM study.
2/2015Efficacy of delayed-release dimethyl fumarate in relapsing-remitting multiple sclerosis: integrated analysis of the phase 3 trials.
12/2014Magnetization transfer ratio in the delayed-release dimethyl fumarate DEFINE study.
9/2014Effects of delayed-release dimethyl fumarate on MRI measures in the Phase 3 DEFINE study.
2/2014Quality of life outcomes with BG-12 (dimethyl fumarate) in patients with relapsing-remitting multiple sclerosis: the DEFINE study.
2/2014Effects of BG-12 (dimethyl fumarate) on health-related quality of life in patients with relapsing-remitting multiple sclerosis: findings from the CONFIRM study.
10/2013Tolerability and pharmacokinetics of delayed-release dimethyl fumarate administered with and without aspirin in healthy volunteers.
10/2013Oral BG-12 (dimethyl fumarate) for relapsing-remitting multiple sclerosis: a review of DEFINE and CONFIRM. Evaluation of: Gold R, Kappos L, Arnold D, et al. Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis. N Engl J Med 2012;367:1098-107; and Fox RJ, Miller DH, Phillips JT, et al. Placebo-controlled phase 3 study of oral BG-12 or glatiramer in multiple sclerosis. N Engl J Med 2012;367:1087-97.
9/2013Clinical efficacy of BG-12 (dimethyl fumarate) in patients with relapsing-remitting multiple sclerosis: subgroup analyses of the DEFINE study.
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Katherine T Dawson Research Topics

Disease

11Relapsing-Remitting Multiple Sclerosis
03/2015 - 10/2008
7Multiple Sclerosis
12/2017 - 09/2012
4Flushing
10/2013 - 10/2008
2Atrophy
03/2015 - 09/2014
2Abdominal Pain (Pain, Abdominal)
09/2012 - 10/2008
1Nausea
09/2012
1Diarrhea
09/2012
1Fatigue
10/2008
1Headache (Headaches)
10/2008

Drug/Important Bio-Agent (IBA)

14Dimethyl FumarateIBA
12/2017 - 10/2008
4Glatiramer Acetate (Copaxone)FDA Link
03/2015 - 09/2012
3FumaratesIBA
03/2015 - 10/2008
1Indicators and Reagents (Reagents)IBA
12/2014
1GadoliniumIBA
09/2014
1GoldIBA
10/2013
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
10/2013
1monomethyl fumarateIBA
10/2013
1ProstaglandinsIBA
10/2013
1Prostaglandin D2IBA
10/2013
1Transaminases (Aminotransferases)IBA
09/2012
1InterferonsIBA
09/2012

Therapy/Procedure

1Therapeutics
03/2015